Tg(ACTB-GLRX)1Dkd
Transgene Detail

Summary

• Symbol: Tg(ACTB-GLRX)1Dkd
• Name: transgene insertion 1, Dipak K Das
• MGI ID: MGI:3775630
• Synonyms: GRX-TG
• Transgene: Tg(ACTB-GLRX)1Dkd Location: unknown
• Alliance: Tg(ACTB-GLRX)1Dkd page

Transgene origin

• Strain of Origin: (C57BL/6 x C3H)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(ACTB-GLRX)1Dkd expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  GLRX (2745)

  Glrx	(MGI:2135625)

• Mutation details: This transgene consists of the human beta-actin promoter driving expression of a human GLRX cDNA. High levels of expression are seen in the heart and skeletal muscle while lower levels of expression are seen in the brain and tongue. (J:131878)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:131878 Malik G, et al., Role of glutaredoxin-1 in cardioprotection: an insight with Glrx1 transgenic and knockout animals. J Mol Cell Cardiol. 2008 Feb;44(2):261-9
• All: 2 reference(s)