Bhlhe40^tm1.1Rhli
Targeted Allele Detail

Summary

• Symbol: Bhlhe40^tm1.1Rhli
• Name: basic helix-loop-helix family, member e40; targeted mutation 1.1, Robert H Lipsky
• MGI ID: MGI:3775803
• Gene: Bhlhe40 Location: Chr6:108637590-108643886 bp, + strand Genetic Position: Chr6, 49.85 cM, cytoband E-F1
• Alliance: Bhlhe40^tm1.1Rhli page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:131834
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Germ-line cre-mediated recombination was used to remove exons 1 through 4. The absence of transcript was confirmed by RT-PCR on hippocampus extracts. (J:131834)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Bhlhe40 Mutation: 51 strains or lines available

References

• Original: J:131834 Jiang X, et al., BHLHB2 controls Bdnf promoter 4 activity and neuronal excitability. J Neurosci. 2008 Jan 30;28(5):1118-30
• All: 4 reference(s)