Cysltr2^tm1Sish
Targeted Allele Detail

Summary

• Symbol: Cysltr2^tm1Sish
• Name: cysteinyl leukotriene receptor 2; targeted mutation 1, Satoshi Ishii
• MGI ID: MGI:3775826
• Gene: Cysltr2 Location: Chr14:73263043-73286554 bp, - strand Genetic Position: Chr14, 38.54 cM
• Alliance: Cysltr2^tm1Sish page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:132275
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• The gene was replaced with a lacZ cassette (Ishii, unpublished). This is a null allele. (J:132275)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cysltr2 Mutation: 33 strains or lines available

References

• Original: J:132275 Jiang W, et al., Endothelial Cysteinyl Leukotriene 2 Receptor Expression Mediates Myocardial Ischemia-Reperfusion Injury. Am J Pathol. 2008 Mar;172(3):592-602
• All: 4 reference(s)