Actl6b^tm1Grc
Targeted Allele Detail

Summary

• Symbol: Actl6b^tm1Grc
• Name: actin-like 6B; targeted mutation 1, Gerald R Crabtree
• MGI ID: MGI:3775841
• Synonyms: BAF53b^-
• Gene: Actl6b Location: Chr5:137551784-137567844 bp, + strand Genetic Position: Chr5, 76.56 cM
• Alliance: Actl6b^tm1Grc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:132101
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 and 3 were replaced with a neo cassette. The absence of protein product was confirmed by silver stain analysis on adult brain nuclear extracts. (J:132101)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Actl6b Mutation: 31 strains or lines available

References

• Original: J:132101 Wu JI, et al., Regulation of dendritic development by neuron-specific chromatin remodeling complexes. Neuron. 2007 Oct 4;56(1):94-108
• All: 5 reference(s)