Sbf2^Gt(XH212)Byg
Gene trapped Allele Detail

Summary

• Symbol: Sbf2^Gt(XH212)Byg
• Name: SET binding factor 2; gene trap XH212, BayGenomics
• MGI ID: MGI:3776016
• Synonyms: Mtmr13^-
• Gene: Sbf2 Location: Chr7:109907220-110214129 bp, - strand Genetic Position: Chr7, 57.7 cM, cytoband F2
• Alliance: Sbf2^Gt(XH212)Byg page

Mutation origin

• Mutant Cell Line: XH212
• Germline Transmission: Earliest citation of germline transmission: J:132044
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1Lxf Vector Type: gene trap
• Mutation details: A beta-geo gene trap was inserted into intron 14. The absence of protein product was confirmed by western blot analysis on sciatic nerve extracts. This is a null allele and a reporter allele. (J:132044)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  XH212	CC200032 ; (MGI Seq Detail)	5' RACE	Chr7:110027395-110040187 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  9 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sbf2 Mutation: 105 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:132044 Tersar K, et al., Mtmr13/Sbf2-deficient mice: an animal model for CMT4B2. Hum Mol Genet. 2007 Dec 15;16(24):2991-3001
• All: 2 reference(s)