Tg(Pomc-EGFP)1Low
Transgene Detail

Summary

• Symbol: Tg(Pomc-EGFP)1Low
• Name: transgene insertion 1, Malcolm J Low
• MGI ID: MGI:3776091
• Synonyms: POMC-EGFP, POMC-GFP
• Transgene: Tg(Pomc-EGFP)1Low Location: unknown
• Alliance: Tg(Pomc-EGFP)1Low page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: EGFP was inserted into the 5' untranslated region of a modified Pomc genomic region that contains 13 kb 5' and 2 kb 3' flanking sequence. The expression pattern recapitulated endogenous Pomc expression in the arcuate nucleus of the hypothalamus. (J:132490)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:132490 Cowley MA, et al., Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus. Nature. 2001 May 24;411(6836):480-4
• All: 90 reference(s)