Ldha^a-m3Neu
Chemically induced Allele Detail

Summary

• Symbol: Ldha^a-m3Neu
• Name: lactate dehydrogenase A; mutation 3, Neuherberg
• MGI ID: MGI:3776263
• Synonyms: Ldh1^3Neu, LDH 9546
• Gene: Ldha Location: Chr7:46491698-46505051 bp, + strand Genetic Position: Chr7, 30.6 cM
• Alliance: Ldha^a-m3Neu page

Mutation origin

• Strain of Origin: (102/El x C3H/El)F1

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Undefined
• Mutation details: ENU mutagenesis resulted in a defect that caused a 42% to 50% reduction of enzyme activity in heterozygous mice. (J:1072)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ldha Mutation: 35 strains or lines available

References

• Original: J:15477 Charles DJ, et al., Linear dose-response relationship of erythrocyte enzyme-activity mutations in offspring of ethylnitrosourea-treated mice. Mutat Res. 1987 Jan;176(1):81-91
• All: 5 reference(s)