Ldha^a-m4Neu
Radiation induced Allele Detail

Summary

• Symbol: Ldha^a-m4Neu
• Name: lactate dehydrogenase A; mutation 4, Neuherberg
• MGI ID: MGI:3776264
• Synonyms: LDH 2534
• Gene: Ldha Location: Chr7:46491698-46505051 bp, + strand Genetic Position: Chr7, 30.6 cM
• Alliance: Ldha^a-m4Neu page

Mutation origin

• Strain of Origin: (102/El x C3H/El)F1

Mutation description

• Allele Type: Radiation induced
• Mutation: Undefined
• Mutation details: Radiation-induced mutagenesis resulted in a mutation that caused a 42% to 50% reduction of enzyme activity in heterozygous mice. (J:1072)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ldha Mutation: 35 strains or lines available

References

• Original: J:1072 Merkle S, et al., Hereditary lactate dehydrogenase A-subunit deficiency as cause of early postimplantation death of homozygotes in Mus musculus. Genetics. 1992 Jun;131(2):413-21
• All: 1 reference(s)