Tg(CD2-Ahr*)NKno
Transgene Detail
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Symbol: |
Tg(CD2-Ahr*)NKno |
Name: |
transgene insertion N, Keiko Nohara |
MGI ID: |
MGI:3776517 |
Synonyms: |
Tg(hCD2-CA-AhR)N |
Transgene: |
Tg(CD2-Ahr*)NKno Location: unknown
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Alliance: |
Tg(CD2-Ahr*)NKno page
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Strain of Origin: |
C57BL/6J x DBA/2
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Transgene Type: |
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Transgenic (Constitutively active, Inserted expressed sequence) |
Mutation: |
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Insertion
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Mutation details: The transgene contains the human CD2 promoter driving expression of a constitutively active mouse aryl hydrocarbon receptor. Line N was estimated to contain 6-7 transgene copies based on Southern blot analysis. Expression was confirmed in spleen and thymus.
(J:97720)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:97720 Nohara K, et al., Constitutively active aryl hydrocarbon receptor expressed specifically in T-lineage cells causes thymus involution and suppresses the immunization-induced increase in splenocytes. J Immunol. 2005 Mar 1;174(5):2770-7 |
All: |
1 reference(s) |
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