Ap3b1^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Ap3b1^m1Btlr
• Name: adaptor-related protein complex 3, beta 1 subunit; mutation 1, Bruce Beutler
• MGI ID: MGI:3776785
• Synonyms: Ap3b1^{bullet gray}, bullet gray
• Gene: Ap3b1 Location: Chr13:94495468-94702825 bp, + strand Genetic Position: Chr13, 49.22 cM
• Alliance: Ap3b1^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation is a G-to-T transversion in the donor splice site of intron 13 (GT -> TT) (position 92056 in Genbank genomic region NC_000079). It is predicted to result in skipping of the 133-nucleotide exon 13 (of 27 total exons) and to shift the reading frame after codon 411, leading to a premature termination codon following codon 412. (J:132673)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ap3b1 Mutation: 96 strains or lines available

References

• Original: J:132673 Rutschmann S, et al., Bullet gray, a new ENU-induced mutation of Ap3b1. MGI Direct Data Submission. 2008
• All: 2 reference(s)