Atcay^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Atcay^m1Btlr
• Name: ataxia, cerebellar, Cayman type; mutation 1, Bruce Beutler
• MGI ID: MGI:3776916
• Synonyms: wobbley
• Gene: Atcay Location: Chr10:81040342-81066667 bp, - strand Genetic Position: Chr10, 39.72 cM
• Alliance: Atcay^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation is a T-to-A transversion in the splice donor site (GT to GA) of intron 4 (position 16060 in the Genbank genomic region NC_000076). It is predicted possibly to result in skipping of exon 4 (of 13 total exons), encoding 222 amino acids, without affecting the reading frame. (J:132743)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Atcay Mutation: 27 strains or lines available

References

• Original: J:132743 Arnold CN, et al., Wobbley, a new allele of atcay, causes progressive defects in gait and coordination. MGI Direct Data Submission. 2008
• All: 1 reference(s)