Bicc1^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Bicc1^m1Btlr
• Name: BicC family RNA binding protein 1; mutation 1, Bruce Beutler
• MGI ID: MGI:3776918
• Synonyms: artemis
• Gene: Bicc1 Location: Chr10:70758662-70995530 bp, - strand Genetic Position: Chr10, 36.75 cM
• Alliance: Bicc1^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation is a C-to-T transition at nucleotide position 275 (Genbank Accession NM_031397) resulting in replacement of threonine by isoleucine at amino acid position 86 (T86I), which resides in the N-terminal K homology RNA-binding domain of the protein. (J:132744)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Bicc1 Mutation: 65 strains or lines available

References

• Original: J:132744 Barnes M, et al., Artemis, an ENU-induced mouse Biocc1 mutation causing polycystic kidneys. MGI Direct Data Submission. 2008
• All: 1 reference(s)