Dkk1^tm1Sia
Targeted Allele Detail

Summary

• Symbol: Dkk1^tm1Sia
• Name: dickkopf WNT signaling pathway inhibitor 1; targeted mutation 1, Shinichi Aizawa
• MGI ID: MGI:3777004
• Synonyms: Dkk1^venus
• Gene: Dkk1 Location: Chr19:30523276-30526896 bp, - strand Genetic Position: Chr19, 25.16 cM, cytoband C2
• Alliance: Dkk1^tm1Sia page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:122557
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• The first and second exon were replaced with a venus and floxed neo cassette. (J:122557)

Expression

In Mice Carrying this Mutation:

11 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dkk1 Mutation: 18 strains or lines available

References

• Original: J:122557 Furushima K, et al., Mouse homologues of Shisa antagonistic to Wnt and Fgf signalings. Dev Biol. 2007 Jun 15;306(2):480-92
• All: 3 reference(s)