Wipf3^tm1Tta
Targeted Allele Detail

Summary

• Symbol: Wipf3^tm1Tta
• Name: WAS/WASL interacting protein family, member 3; targeted mutation 1, Tadaomi Takenawa
• MGI ID: MGI:3777008
• Synonyms: CD16^-
• Gene: Wipf3 Location: Chr6:54406588-54480753 bp, + strand Genetic Position: Chr6, 26.93 cM
• Alliance: Wipf3^tm1Tta page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:132529
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced with a nuclear-localization-tagged lacZ cassette, xanthine/guanine phosphoribosyl transferase and a neo cassette. The absence of protein product was confirmed by western blot analysis on brain, spleen and testis extracts. (J:132529)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wipf3 Mutation: 24 strains or lines available

References

• Original: J:132529 Suetsugu S, et al., Male-specific sterility caused by the loss of CR16. Genes Cells. 2007 Jun;12(6):721-33
• All: 1 reference(s)