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Wipf3tm1Tta
Targeted Allele Detail
Summary
Symbol: Wipf3tm1Tta
Name: WAS/WASL interacting protein family, member 3; targeted mutation 1, Tadaomi Takenawa
MGI ID: MGI:3777008
Synonyms: CD16-
Gene: Wipf3  Location: Chr6:54406588-54480753 bp, + strand  Genetic Position: Chr6, 26.93 cM
Alliance: Wipf3tm1Tta page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:132529
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 was replaced with a nuclear-localization-tagged lacZ cassette, xanthine/guanine phosphoribosyl transferase and a neo cassette. The absence of protein product was confirmed by western blot analysis on brain, spleen and testis extracts. (J:132529)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Wipf3 Mutation:  24 strains or lines available
References
Original:  J:132529 Suetsugu S, et al., Male-specific sterility caused by the loss of CR16. Genes Cells. 2007 Jun;12(6):721-33
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory