Srrt^tm1Bfk
Targeted Allele Detail

Summary

• Symbol: Srrt^tm1Bfk
• Name: serrate RNA effector molecule homolog (Arabidopsis); targeted mutation 1, Ben F Koop
• MGI ID: MGI:3777245
• Gene: Srrt Location: Chr5:137293973-137305928 bp, - strand Genetic Position: Chr5, 76.33 cM
• Alliance: Srrt^tm1Bfk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:132672
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A fragment including the proximal promoter and exons 1 - 3 was replaced with floxed PGK-neo cassette via homologous recombination. The neo cassette was removed via in vivo Cre mediated recombination. (J:132672)

Expression

In Mice Carrying this Mutation:

4 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Srrt Mutation: 55 strains or lines available

References

• Original: J:132672 Wilson MD, et al., ARS2 is a conserved eukaryotic gene essential for early mammalian development. Mol Cell Biol. 2008 Mar;28(5):1503-14
• All: 1 reference(s)