Glra2^tm1Lex
Targeted Allele Detail

Summary

• Symbol: Glra2^tm1Lex
• Name: glycine receptor, alpha 2 subunit; targeted mutation 1, Lexicon Genetics
• MGI ID: MGI:3777271
• Gene: Glra2 Location: ChrX:163912013-164110389 bp, - strand Genetic Position: ChrX, 76.75 cM
• Alliance: Glra2^tm1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:132622
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified
• Project Collection: Lexicon

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced with a lacZ/neo cassette. The absence of protein product was confirmed by immunohistochemistry. (J:132622)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Glra2 Mutation: 9 strains or lines available

References

• Original: J:132622 Weiss J, et al., Glycinergic input of small-field amacrine cells in the retinas of wildtype and glycine receptor deficient mice. Mol Cell Neurosci. 2008 Jan;37(1):40-55
• All: 3 reference(s)