Tg(Neurog1-cre/ERT2)1Good
Transgene Detail

Summary

• Symbol: Tg(Neurog1-cre/ERT2)1Good
• Name: transgene insertion 1, Lisa V Goodrich
• MGI ID: MGI:3777275
• Synonyms: Neurog1^CreER, Ngn1^CreER, Ngn1-CreER^T2, Ngn-CreERT2, Tg(Neurog1-cre/ESR1)1Good
• Transgene: Tg(Neurog1-cre/ERT2)1Good Location: unknown
• Alliance: Tg(Neurog1-cre/ERT2)1Good page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Neurog1-cre/ERT2)1Good expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Neurog1

• Mutation details: A transgene was constructed where cre recombinase fused to the ligand-binding domain of a mutant human estrogen receptor was placed under the control of the upstream promoter and the downstream untranslated region of the Neurog1 gene. Cre activity was detected in cochlear ganglion neurons of transgenic mice when crossed with a cre-reporter strain and dosing with tamoxifen. (J:130813)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Neurog1 (species not specified) Summary of all recombinase alleles driven by Neurog1. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:130813 Koundakjian EJ, et al., Auditory neurons make stereotyped wiring decisions before maturation of their targets. J Neurosci. 2007 Dec 19;27(51):14078-88
• All: 27 reference(s)