Lfng^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Lfng^m1Btlr
• Name: LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; mutation 1, Bruce Beutler
• MGI ID: MGI:3777551
• Synonyms: zigzag
• Gene: Lfng Location: Chr5:140593096-140601300 bp, + strand Genetic Position: Chr5, 79.15 cM
• Alliance: Lfng^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation is a T-to-C transition at nucleotide position 686 (Genbank Accession NM_008494), in the last of four exons, resulting in replacement of a conserved valine by alanine at amino acid position 204 (V204A) of the protein. (J:132741)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Lfng Mutation: 32 strains or lines available

References

• Original: J:132741 Eidenschenk C, et al., Zigzag, a viable mouse Lfng mutation affecting the axial skeleton. MGI Direct Data Submission. 2008
• All: 1 reference(s)