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Wnt7am1Btlr
Chemically induced Allele Detail
Summary
Symbol: Wnt7am1Btlr
Name: wingless-type MMTV integration site family, member 7A; mutation 1, Bruce Beutler
MGI ID: MGI:3777583
Synonyms: gimpy
Gene: Wnt7a  Location: Chr6:91340963-91388335 bp, - strand  Genetic Position: Chr6, 40.45 cM
Alliance: Wnt7am1Btlr page
Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: Beutler Mutagenetix
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsThe mutation is a T-to-A transversion at nucleotide position 1275 (Genbank Accession NM_009527), resulting in replacement of cysteine by serine at amino acid position 339 of the protein (C339S). (J:132753)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Wnt7a Mutation:  26 strains or lines available
References
Original:  J:132753 Crozat k, et al., Gimpy, an ENU-induced mouse mutant with abnormal extremities. MGI Direct Data Submission. 2008;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory