Wnt7a^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Wnt7a^m1Btlr
• Name: wingless-type MMTV integration site family, member 7A; mutation 1, Bruce Beutler
• MGI ID: MGI:3777583
• Synonyms: gimpy
• Gene: Wnt7a Location: Chr6:91340963-91388335 bp, - strand Genetic Position: Chr6, 40.45 cM
• Alliance: Wnt7a^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation is a T-to-A transversion at nucleotide position 1275 (Genbank Accession NM_009527), resulting in replacement of cysteine by serine at amino acid position 339 of the protein (C339S). (J:132753)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Wnt7a Mutation: 26 strains or lines available

References

• Original: J:132753 Crozat k, et al., Gimpy, an ENU-induced mouse mutant with abnormal extremities. MGI Direct Data Submission. 2008
• All: 1 reference(s)