Tg(MUC1)79.24Gend
Transgene Detail

Summary

• Symbol: Tg(MUC1)79.24Gend
• Name: transgene insertion 79.24, Sandra J Gendler
• MGI ID: MGI:3777621
• Synonyms: MUC1.Tg
• Transgene: Tg(MUC1)79.24Gend Location: unknown
• Alliance: Tg(MUC1)79.24Gend page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(MUC1)79.24Gend expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  MUC1 (4582)

  Muc1	(MGI:97231)

• Mutation details: A 10.6 kb genomic fragment containing the entire human MUC1 gene sequence, as well as 1.5 kb of 5' sequence and 800 bases of 3'sequence was isolated and injected into pronuclei of fertilized C57BL/6 eggs. (J:128899)

Disease models

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:128899 Rowse GJ, et al., Tolerance and immunity to MUC1 in a human MUC1 transgenic murine model. Cancer Res. 1998 Jan 15;58(2):315-21
• All: 35 reference(s)