Pnp^g
Chemically induced Allele Detail

Summary

• Symbol: Pnp^g
• Name: purine-nucleoside phosphorylase; NP-1G
• MGI ID: MGI:3777975
• Synonyms: Np-1^g
• Gene: Pnp Location: Chr14:51181760-51190869 bp, + strand Genetic Position: Chr14, 26.31 cM, cytoband B-C1
• Alliance: Pnp^g page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This allele was identified in the progeny of a cross between ENU mutagenized C57BL/6J males and C3H/HeHa females. A T to C transition occurred at nucleotide 46 resulting in a W16R amino acid change in the resulting protein. (J:522, J:39328)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pnp Mutation: 29 strains or lines available

References

• Original: J:522 Snyder FF, Genetic models of purine nucleoside phosphorylase deficiency in the mouse. Adv Exp Med Biol. 1991;309B:137-40
• All: 3 reference(s)