Lgals9^tm1Glp
Targeted Allele Detail

Summary

• Symbol: Lgals9^tm1Glp
• Name: lectin, galactose binding, soluble 9; targeted mutation 1, Mitsuomi Hirashima
• MGI ID: MGI:3778171
• Synonyms: Gal-9^-
• Gene: Lgals9 Location: Chr11:78853805-78875750 bp, - strand Genetic Position: Chr11, 46.74 cM
• Alliance: Lgals9^tm1Glp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:132889
• Parent Cell Line: iTL1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exon 1 was disrupted by homologous recombination. The entire coding region is removed. (J:132889)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lgals9 Mutation: 33 strains or lines available

References

• Original: J:132889 Seki M, et al., Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis. Clin Immunol. 2008 Apr;127(1):78-88
• All: 14 reference(s)