Txnip^tm1Road
Targeted Allele Detail

Summary

• Symbol: Txnip^tm1Road
• Name: thioredoxin interacting protein; targeted mutation 1, Roger Davis
• MGI ID: MGI:3778275
• Synonyms: Txnip^fl
• Gene: Txnip Location: Chr3:96465273-96469173 bp, + strand Genetic Position: Chr3, 41.93 cM, cytoband F2.2
• Alliance: Txnip^tm1Road page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:132756
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed neo cassette was inserted downstream of exon 8 and an additional loxP site was inserted downstream of exon 1. Exons 2 through 8 are floxed. (J:132756)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Txnip Mutation: 49 strains or lines available

References

• Original: J:132756 Hui ST, et al., Txnip balances metabolic and growth signaling via PTEN disulfide reduction. Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3921-6
• All: 10 reference(s)