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Edaraddcr-Btlr
Chemically induced Allele Detail
Summary
Symbol: Edaraddcr-Btlr
Name: EDAR associated via death domain; crinkled Bruce Beutler
MGI ID: MGI:3778290
Synonyms: achtung, Edaraddm1Btlr
Gene: Edaradd  Location: Chr13:12487513-12535319 bp, - strand  Genetic Position: Chr13, 4.77 cM
Alliance: Edaraddcr-Btlr page
Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: Beutler Mutagenetix
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsThe mutation is an A-to-T transversion at nucleotide position 813, in the last of 6 exons, resulting in replacement of isoleucine by phenylalanine at amino acid position 105 (I105F), at the N-terminal border of the death domain of the protein. (J:133274)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Edaradd Mutation:  16 strains or lines available
References
Original:  J:133274 Du X, et al., Achtung is an allele of Edaradd, which functions in the EDAR signaling pathway. MGI Direct Data Submission. 2008;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory