Edaradd^cr-Btlr
Chemically induced Allele Detail

Summary

• Symbol: Edaradd^cr-Btlr
• Name: EDAR associated via death domain; crinkled Bruce Beutler
• MGI ID: MGI:3778290
• Synonyms: achtung, Edaradd^m1Btlr
• Gene: Edaradd Location: Chr13:12487513-12535319 bp, - strand Genetic Position: Chr13, 4.77 cM
• Alliance: Edaradd^cr-Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation is an A-to-T transversion at nucleotide position 813, in the last of 6 exons, resulting in replacement of isoleucine by phenylalanine at amino acid position 105 (I105F), at the N-terminal border of the death domain of the protein. (J:133274)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Edaradd Mutation: 16 strains or lines available

References

• Original: J:133274 Du X, et al., Achtung is an allele of Edaradd, which functions in the EDAR signaling pathway. MGI Direct Data Submission. 2008
• All: 1 reference(s)