Tll2^tm1.1Sjl
Targeted Allele Detail

Summary

• Symbol: Tll2^tm1.1Sjl
• Name: tolloid-like 2; targeted mutation 1.1, Se-Jin Lee
• MGI ID: MGI:3778379
• Gene: Tll2 Location: Chr19:41071192-41195274 bp, - strand Genetic Position: Chr19, 34.39 cM
• Alliance: Tll2^tm1.1Sjl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:132807
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 7 was removed by germ-line, cre-mediated recombination. Transcript levels undetectable by northern blot analysis on brain extracts. (J:132807)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tll2 Mutation: 55 strains or lines available

References

• Original: J:132807 Lee SJ, Genetic analysis of the role of proteolysis in the activation of latent myostatin. PLoS One. 2008;3(2):e1628
• All: 1 reference(s)