Bmftm1Ast
Targeted Allele Detail
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Symbol: |
Bmftm1Ast |
Name: |
BCL2 modifying factor; targeted mutation 1, Andreas Strasser |
MGI ID: |
MGI:3778609 |
Synonyms: |
Bmftm1Anvi |
Gene: |
Bmf Location: Chr2:118359238-118380168 bp, - strand Genetic Position: Chr2, 59.4 cM, cytoband E5
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Alliance: |
Bmftm1Ast page
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Germline Transmission: |
Earliest citation of germline transmission:
J:133084
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Parent Cell Line: |
Bruce 4 (ES Cell)
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Strain of Origin: |
B6.Cg-Thy1a
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: A floxed neo cassette was inserted downstream of exon 4 and an additional loxP site was inserted downstream of exon 2. The neo cassette was removed by germ-line, cre-mediated recombination resulting in a floxed exon 3 and 4.
(J:133084)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Bmf Mutation: |
21 strains or lines available
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Original: |
J:133084 Labi V, et al., Loss of the BH3-only protein Bmf impairs B cell homeostasis and accelerates gamma irradiation-induced thymic lymphoma development. J Exp Med. 2008 Mar 17;205(3):641-55 |
All: |
1 reference(s) |
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