Gata4^tm1(cre)Svs
Targeted Allele Detail

Summary

• Symbol: Gata4^tm1(cre)Svs
• Name: GATA binding protein 4; targeted mutation 1, David S Silversides
• MGI ID: MGI:3778758
• Synonyms: G4-RFP, Gata4^Cre
• Gene: Gata4 Location: Chr14:63436371-63509141 bp, - strand Genetic Position: Chr14, 33.24 cM
• Alliance: Gata4^tm1(cre)Svs page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:132976
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Recombinase, Reporter)
• Mutations: Insertion, Intragenic deletion
• Gata4^tm1(cre)Svs expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Gata4 (MGI:95664)

• Exon 2 was replaced with a cassette containing dsRed2, IRES, cre and a neo gene. (J:132976)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Gata4 (mouse) Summary of all recombinase alleles driven by Gata4. Alliance mouse Gata4 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gata4 Mutation: 36 strains or lines available

References

• Original: J:132976 Pilon N, et al., Novel pre- and post-gastrulation expression of Gata4 within cells of the inner cell mass and migratory neural crest cells. Dev Dyn. 2008 Apr;237(4):1133-43
• All: 5 reference(s)