Wnt6^tm1Akis
Targeted Allele Detail

Summary

• Symbol: Wnt6^tm1Akis
• Name: wingless-type MMTV integration site family, member 6; targeted mutation 1, Andreas Kispert
• MGI ID: MGI:3778772
• Synonyms: Wnt6^neo
• Gene: Wnt6 Location: Chr1:74811051-74824481 bp, + strand Genetic Position: Chr1, 38.54 cM
• Alliance: Wnt6^tm1Akis page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:132979
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 3 and 4 were replaced with a floxed neo cassette. (J:132979, J:193969)

Expression

In Mice Carrying this Mutation:	5 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wnt6 Mutation: 13 strains or lines available

References

• Original: J:132979 Potok MA, et al., WNT signaling affects gene expression in the ventral diencephalon and pituitary gland growth. Dev Dyn. 2008 Apr;237(4):1006-20
• All: 2 reference(s)