Tg(Isl1-EGFP*)1Slp
Transgene Detail

Summary

• Symbol: Tg(Isl1-EGFP*)1Slp
• Name: transgene insertion 1, Samuel L Pfaff
• MGI ID: MGI:3779015
• Synonyms: ISL^MN:GFP-F
• Transgene: Tg(Isl1-EGFP*)1Slp Location: unknown
• Alliance: Tg(Isl1-EGFP*)1Slp page

Transgene origin

• Strain of Origin: (BALB/c x C57BL/6)F1

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: A minimal CMV promoter fused to the medial-class spinal motor neuron axons (MMCm) specific enhancer of Isl1 containing a crest1 regulatory element (SE1) was used to drive expression of a farnesylated EGFP followed by an SV40 adenylation signal and flanked by 1.2 kb insulator sequence. No line information was given. (J:132726)

Disease models

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:132726 Lewcock JW, et al., The ubiquitin ligase Phr1 regulates axon outgrowth through modulation of microtubule dynamics. Neuron. 2007 Nov 21;56(4):604-20
• All: 24 reference(s)