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Tg(CAG-rtTA)72Wiek
Transgene Detail
Summary
Symbol: Tg(CAG-rtTA)72Wiek
Name: transgene insertion 72, Maria T Wiekowski
MGI ID: MGI:3779019
Synonyms: CAG-rtTA, CMV-Betaactin-rtTA, Tg(ACTB-rtTA)72Wiek
Transgene: Tg(CAG-rtTA)72Wiek  Location: unknown  
Alliance: Tg(CAG-rtTA)72Wiek page
Transgene
origin
Strain of Origin:  (C57BL/6J X DBA/2)F2
Transgene
description
Transgene Type:    Transgenic (Transactivator)
Mutation:    Insertion
 
Mutation detailsThe transgene construct contains the rtTA cDNA driven by the CMV enhancer/chicken beta-actin promoter. The rabbit beta-globin polyadenylation signal is also part of the transgene construct. Eight transgenic lines were derived, and line 72 was analyzed further based on high expression of activator transgene expression. (J:73096)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:73096 Wiekowski MT, et al., Disruption of neutrophil migration in a conditional transgenic model: evidence for CXCR2 desensitization in vivo. J Immunol. 2001 Dec 15;167(12):7102-10
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory