Myf5^{tm1.1(cre)Mrc}
Targeted Allele Detail

Summary

• Symbol: Myf5^{tm1.1(cre)Mrc}
• Name: myogenic factor 5; targeted mutation 1.1, Mario R Capecchi
• MGI ID: MGI:3783303
• Synonyms: Myf5-Cre-NN, Myf5-NN^-
• Gene: Myf5 Location: Chr10:107318769-107321995 bp, - strand Genetic Position: Chr10, 55.95 cM
• Alliance: Myf5^{tm1.1(cre)Mrc} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:133338
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Myf5^{tm1.1(cre)Mrc} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Myf5 (MGI:97252)

• Mutation details: Germ-line, flp-mediated recombination was used to remove the neo cassette. Expression of the endogenous gene is normal. (J:133338)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Myf5 (mouse) Summary of all recombinase alleles driven by Myf5. Comparative matrix view of recombinase activities Alliance mouse Myf5 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Myf5 Mutation: 17 strains or lines available

References

• Original: J:133338 Haldar M, et al., Two cell lineages, myf5 and myf5-independent, participate in mouse skeletal myogenesis. Dev Cell. 2008 Mar;14(3):437-45
• All: 7 reference(s)