Gngt1^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Gngt1^tm1Dgen
• Name: guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1; targeted mutation 1, Deltagen
• MGI ID: MGI:3783323
• Synonyms: Ggamma1^-
• Gene: Gngt1 Location: Chr6:3993792-3997436 bp, + strand Genetic Position: Chr6, 1.81 cM, cytoband A1
• Alliance: Gngt1^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:133487
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The coding region of exon 1 and 2 were replaced with an IRES-lacZ-neo cassette. This is a null allele because it lacks the coding region. (J:133487)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gngt1 Mutation: 14 strains or lines available

References

• Original: J:133487 Lobanova ES, et al., Transducin gamma-subunit sets expression levels of alpha- and beta-subunits and is crucial for rod viability. J Neurosci. 2008 Mar 26;28(13):3510-20
• All: 6 reference(s)