Tg(Myh6-Ncor2*)1Kjep
Transgene Detail

Summary

• Symbol: Tg(Myh6-Ncor2*)1Kjep
• Name: transgene insertion 1, Kristen Jepsen
• MGI ID: MGI:3783599
• Synonyms: alpha-MHC-DN-SMRT
• Transgene: Tg(Myh6-Ncor2*)1Kjep Location: unknown
• Alliance: Tg(Myh6-Ncor2*)1Kjep page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Dominant negative, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: This transgene contains the Myh6 promoter driving myocyte-specific expression of a dominant negative Ncor2 with an N-terminal HA-tag and a nuclear localization signal. The dominant negative consists of the nucleotides from position 1500 to the stop codon that encode the nuclear receptor interaction domains. No line information was given. (J:132982)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:132982 Jepsen K, et al., Cooperative regulation in development by SMRT and FOXP1. Genes Dev. 2008 Mar 15;22(6):740-5
• All: 1 reference(s)