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Tg(Lck-Socs3)1Kubo
Transgene Detail
Summary
Symbol: Tg(Lck-Socs3)1Kubo
Name: transgene insertion 1, Masato Kubo
MGI ID: MGI:3783708
Synonyms: SOCS3 Tg
Transgene: Tg(Lck-Socs3)1Kubo  Location: unknown  
Alliance: Tg(Lck-Socs3)1Kubo page
Transgene
origin
Strain of Origin:  Not Applicable
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Lck-Socs3)1Kubo expresses 1 gene
 
Mutation detailsThis transgene contains the Lck promoter with an Emu enhancer driving T-cell specific expression of a myc-tagged Socs3. Four identical lines were created and no line numbers were given. Expression of the myc-tagged transgene is 5 to 10 times higher than endogenous expression. (J:128797)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:128797 Matsumoto A, et al., A role of suppressor of cytokine signaling 3 (SOCS3/CIS3/SSI3) in CD28-mediated interleukin 2 production. J Exp Med. 2003 Feb 17;197(4):425-36
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory