Tg(Eno2-APP*751)10Cord
Transgene Detail

Summary

• Symbol: Tg(Eno2-APP*751)10Cord
• Name: transgene insertion 10, Barbara Cordell
• MGI ID: MGI:3784388
• Synonyms: NSE:beta-APP751
• Transgene: Tg(Eno2-APP*751)10Cord Location: unknown
• Alliance: Tg(Eno2-APP*751)10Cord page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Eno2-APP*751)10Cord expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  APP (351)

  App	(MGI:88059)

• Mutation details: The rat Enos2 promoter drives neural specific expression of the human APP variant APP751 that contains the Kunitz serine protease domain. Three lines were created (lines 10, 11 and 24). Line 10 was chosen as the representative line. (J:127065)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:127065 Quon D, et al., Formation of beta-amyloid protein deposits in brains of transgenic mice. Nature. 1991 Jul 18;352(6332):239-41
• All: 2 reference(s)