Mlph^ln-Btlr
Chemically induced Allele Detail

Summary

• Symbol: Mlph^ln-Btlr
• Name: melanophilin; leaden Bruce Beutler
• MGI ID: MGI:3784966
• Synonyms: koala, Mlph^m1Btlr
• Gene: Mlph Location: Chr1:90842807-90878864 bp, + strand Genetic Position: Chr1, 45.73 cM
• Alliance: Mlph^ln-Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation is an A-to-G transition at nucleotide position 18194 (Genbank genomic region NC_000067), near the 3' end of the sixth intron, that may impair the intron 6 acceptor splice site. Sequence analysis of Mlph cDNA from koala mutants has not been done; the effect of the mutation on transcript processing or protein translation is not known. (J:133625)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mlph Mutation: 38 strains or lines available

References

• Original: J:133625 Arnold CN, et al., Koala is an allele of Mlph and displays pigmentation defects. MGI Direct Data Submission. 2008
• All: 1 reference(s)