Slc45a2^uw-Btlr
Chemically induced Allele Detail

Summary

• Symbol: Slc45a2^uw-Btlr
• Name: solute carrier family 45, member 2; underwhite Bruce Beutler
• MGI ID: MGI:3784977
• Synonyms: cardigan, Slc45a2^m1Btlr
• Gene: Slc45a2 Location: Chr15:11000807-11029319 bp, + strand Genetic Position: Chr15, 5.4 cM
• Alliance: Slc45a2^uw-Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: The mutation corresponds to a C-to-A transversion at nucleotide position 1094, in the 4th of 7 total exons, that creates a premature stop codon in place of serine at amino acid position 333 (S333Ter), in the 7th of 12 transmembrane domains, predicted to delete 297 amino acids from the protein's C-terminus. (J:133628)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc45a2 Mutation: 55 strains or lines available

References

• Original: J:133628 Blasius A, et al., Cardigan is an allele of Slc45a2 and displays pigmentation defects. MGI Direct Data Submission. 2008
• All: 1 reference(s)