Enpp1^asj
Chemically induced Allele Detail

Summary

• Symbol: Enpp1^asj
• Name: ectonucleotide pyrophosphatase/phosphodiesterase 1; ages with stiffened joints
• MGI ID: MGI:3785162
• Gene: Enpp1 Location: Chr10:24513812-24588057 bp, - strand Genetic Position: Chr10, 12.26 cM
• Alliance: Enpp1^asj page

Stiffening of the joints in Enpp1^asj/Enpp1^asj (right) mice, particularly in the forepaws

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This ENU induced mutation was found to be an exon 7 T to A point mutation at position 737, predicted to change a valine to an aspartic acid. (J:174912)

Disease models

Expression

In Structures Affected by this Mutation:

25 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Enpp1 Mutation: 11 strains or lines available

References

• Original: J:174912 Harris BS, et al., Ages with stiffened joints, A new mutation in Enpp1. MGI Direct Data Submission. 2011
• All: 21 reference(s)