Tg(Ins2-E3*704)2Dvs
Transgene Detail
|
|
| Symbol: |
Tg(Ins2-E3*704)2Dvs |
| Name: |
transgene insertion 2, David V Serreze |
| MGI ID: |
MGI:3785496 |
| Synonyms: |
DL704, RIPE3704 |
| Transgene: |
Tg(Ins2-E3*704)2Dvs Location: unknown
|
| Alliance: |
Tg(Ins2-E3*704)2Dvs page
|
|
|
|
| Transgene Type: |
|
Transgenic (Inserted expressed sequence) |
| Mutation: |
|
Insertion
|
| |
|
Mutation details: The rat insulin promoter was placed upstream of the adenovirus early region 3 (E3) with a 202-bp deletion of the gp19K gene and the sequences for the 10.4K, 14.5K, 14.7K (and 11.6K) genes retained. This construct was injected into NOD/ShiLtDvs oocytes. RT-PCR analysis of mRNA from pancreatic beta cells of mice bearing this transgene demonstrates expression of the 10.4K, 14.5K, 14.7K and 11.6K genes, but detects no gp19 transcripts.
(J:83195)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
|
|
| Original: |
J:83195 Pierce MA, et al., Adenovirus early region 3 antiapoptotic 10.4K, 14.5K, and 14.7K genes decrease the incidence of autoimmune diabetes in NOD mice. Diabetes. 2003 May;52(5):1119-27 |
| All: |
1 reference(s) |
|
Analysis Tools
