Tg(Ins2-E3*309)5Dvs
Transgene Detail

Summary

• Symbol: Tg(Ins2-E3*309)5Dvs
• Name: transgene insertion 5, David V Serreze
• MGI ID: MGI:3785516
• Synonyms: DL309, RIPE3DL309
• Transgene: Tg(Ins2-E3*309)5Dvs Location: unknown
• Alliance: Tg(Ins2-E3*309)5Dvs page

Transgene origin

• Strain of Origin: NOD/ShiLtDvs

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The rat insulin promoter was placed upstream of a mutant adenovirus early region (E3) sequences with a 750bp deletion that disrupts the 10.4K, 14.5K, and 14.7K genes, and a 6bp deletion in the 6.7K gene, leaving the gp19K and 11.6K genes expressed. (J:83195)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:83195 Pierce MA, et al., Adenovirus early region 3 antiapoptotic 10.4K, 14.5K, and 14.7K genes decrease the incidence of autoimmune diabetes in NOD mice. Diabetes. 2003 May;52(5):1119-27
• All: 1 reference(s)