Glis2^tm1Amj
Targeted Allele Detail

Summary

• Symbol: Glis2^tm1Amj
• Name: GLIS family zinc finger 2; targeted mutation 1, Anton M Jetten
• MGI ID: MGI:3785519
• Synonyms: Glis2^mut
• Gene: Glis2 Location: Chr16:4412577-4442788 bp, + strand Genetic Position: Chr16, 2.45 cM, cytoband A1-B1
• Alliance: Glis2^tm1Amj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:134208
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 6 was replaced with a neo cassette resulting in a truncation of the protein product such that the fourth and fifth zinc finger motifs are absent. (J:134208)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Glis2 Mutation: 102 strains or lines available

References

• Original: J:134208 Kim YS, et al., Kruppel-like zinc finger protein Glis2 is essential for the maintenance of normal renal functions. Mol Cell Biol. 2008 Apr;28(7):2358-67
• All: 4 reference(s)