Tg(Jam2-cre/ERT2)2Jrs
Transgene Detail

Summary

• Symbol: Tg(Jam2-cre/ERT2)2Jrs
• Name: transgene insertion 2, Joshua R Sanes
• MGI ID: MGI:3785734
• Synonyms: JAM-B-CreER, JAMB-CreER, Tg(Jam2-cre/ESR1)1Jrs
• Transgene: Tg(Jam2-cre/ERT2)2Jrs Location: unknown
• Alliance: Tg(Jam2-cre/ERT2)2Jrs page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Jam2-cre/ERT2)2Jrs expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Jam2

• Mutation details: A tamoxifen-inducible form of cre recombinase and a frt-lanked neomycin selection cassette was put under the control of Jam2 promoter sequences. Transgenic founder mice were crossed with Flpe transgenic mice to remove the neomycin selection cassette. Expression of Cre was confirmed in a subset of retinal neurons upon tamoxifen induction. (J:134167)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Jam2 (species not specified) Summary of all recombinase alleles driven by Jam2. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:134167 Kim IJ, et al., Molecular identification of a retinal cell type that responds to upward motion. Nature. 2008 Mar 27;452(7186):478-82
• All: 17 reference(s)