Ppm1l^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Ppm1l^tm1Dgen
• Name: protein phosphatase 1 (formerly 2C)-like; targeted mutation 1, Deltagen
• MGI ID: MGI:3785735
• Gene: Ppm1l Location: Chr3:69224251-69468131 bp, + strand Genetic Position: Chr3, 32.21 cM
• Alliance: Ppm1l^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:134171
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 183 bp segment of the open reading frame upstream of the translation stop codon was replaced with a 6894 bp IRES-lacZ reporter and neo cassette. (J:134171)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ppm1l Mutation: 26 strains or lines available

References

• Original: J:134171 Chen Y, et al., Variations in DNA elucidate molecular networks that cause disease. Nature. 2008 Mar 27;452(7186):429-35
• All: 1 reference(s)