Tg(CD2-Ifngr2)2Pbro
Transgene Detail

Summary

• Symbol: Tg(CD2-Ifngr2)2Pbro
• Name: transgene insertion 2, Paul B Rothman
• MGI ID: MGI:3785869
• Synonyms: IFN-gammaR2 TG2
• Transgene: Tg(CD2-Ifngr2)2Pbro Location: unknown
• Alliance: Tg(CD2-Ifngr2)2Pbro page

Transgene origin

• Strain of Origin: (C57BL/6 x CBA/J)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CD2-Ifngr2)2Pbro expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ifngr2 (MGI:107654)

• Mutation details: The sequence encoding mouse IFNGR2 was placed under the control of the human CD2 promoter and enhancer and this construct was microinjected into (C57BL/6 x CBA/J) oocytes. Seven copies integrated in this insertion. (J:134448)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:134448 Tau GZ, et al., Interferon gamma signaling alters the function of T helper type 1 cells. J Exp Med. 2000 Oct 2;192(7):977-86
• All: 2 reference(s)