Tgfbr2^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Tgfbr2^tm1Dgen
• Name: transforming growth factor, beta receptor II; targeted mutation 1, Deltagen
• MGI ID: MGI:3785874
• Synonyms: Tgfbr2^-
• Gene: Tgfbr2 Location: Chr9:115916763-116004431 bp, - strand Genetic Position: Chr9, 68.39 cM
• Alliance: Tgfbr2^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:99304
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• 106 bp of the open reading frame in exon 5 was replaced with an IRES-lacZ-neo cassette. (J:99304)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tgfbr2 Mutation: 40 strains or lines available

References

• Original: J:99304 Schadt EE, et al., An integrative genomics approach to infer causal associations between gene expression and disease. Nat Genet. 2005 Jul;37(7):710-7
• All: 2 reference(s)