Tg(CAG-Lama1)12Mdur
Transgene Detail

Summary

• Symbol: Tg(CAG-Lama1)12Mdur
• Name: transgene insertion 12, Madeleine Durbeej
• MGI ID: MGI:3789205
• Synonyms: LNalpha1TG
• Transgene: Tg(CAG-Lama1)12Mdur Location: unknown
• Alliance: Tg(CAG-Lama1)12Mdur page

Transgene origin

• Strain of Origin: CBA x C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-Lama1)12Mdur expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Lama1 (MGI:99892)

• Mutation details: The chicken beta-actin promoter modified with the CMV enhancer (CAG) was used to drive ubiquitous expression of mouse Lama1. Thirteen founder mice were identified, 5 of which exhibited expression in the skeletal muscle. Line 12 exhibited the highest level skeletal muscle expression and was chosen for further analysis. (J:92093)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:92093 Gawlik K, et al., Laminin alpha1 chain reduces muscular dystrophy in laminin alpha2 chain deficient mice. Hum Mol Genet. 2004 Aug 15;13(16):1775-84
• All: 6 reference(s)