Tg(Camk2a-Gpr85)1Mima
Transgene Detail

Summary

• Symbol: Tg(Camk2a-Gpr85)1Mima
• Name: transgene insertion 1, Mitsuyuki Matsumoto
• MGI ID: MGI:3789985
• Synonyms: SREB2 Tg
• Transgene: Tg(Camk2a-Gpr85)1Mima Location: unknown
• Alliance: Tg(Camk2a-Gpr85)1Mima page

Transgene origin

• Strain of Origin: (C57BL x DBA)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Camk2a-Gpr85)1Mima expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Gpr85 (MGI:1927851)

• Mutation details: The mouse Camk2a promoter was used to drive expression of Gpr85 in postnatal forebrain neurons. Two lines were created, one with 2-fold over-expression in the brain and the other with 4-fold over-expression in the brain. The former is designated as line 1. (J:134303)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:134303 Matsumoto M, et al., The evolutionarily conserved G protein-coupled receptor SREB2/GPR85 influences brain size, behavior, and vulnerability to schizophrenia. Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):6133-8
• All: 2 reference(s)