Cd200r1^tm1.1Rmgo
Targeted Allele Detail

Summary

• Symbol: Cd200r1^tm1.1Rmgo
• Name: CD200 receptor 1; targeted mutation 1.1, Reg M Gorczynski
• MGI ID: MGI:3790100
• Gene: Cd200r1 Location: Chr16:44586141-44615341 bp, + strand Genetic Position: Chr16, 29.08 cM, cytoband B5
• Alliance: Cd200r1^tm1.1Rmgo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:135069
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Germ line, cre mediated recombination was used to remove exons 2 through 4. The absence of cell surface protein expression was confirmed by FACS analysis of splenocytes or bone marrow cells. (J:135069)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd200r1 Mutation: 33 strains or lines available

References

• Original: J:135069 Boudakov I, et al., Mice lacking CD200R1 show absence of suppression of lipopolysaccharide-induced tumor necrosis factor-alpha and mixed leukocyte culture responses by CD200. Transplantation. 2007 Jul 27;84(2):251-7
• All: 9 reference(s)