Fermt2^tm1Ref
Targeted Allele Detail

Summary

• Symbol: Fermt2^tm1Ref
• Name: fermitin family member 2; targeted mutation 1, Reinhard Fassler
• MGI ID: MGI:3790102
• Synonyms: K2^-, kindlin-2^-
• Gene: Fermt2 Location: Chr14:45696252-45767575 bp, - strand Genetic Position: Chr14, 22.97 cM
• Alliance: Fermt2^tm1Ref page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:134768
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: An IRES-lacZ-neo cassette was inserted into exon 2. The absence of protein product was confirmed by western blot analysis on ES cell lines. (J:134768)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fermt2 Mutation: 32 strains or lines available

References

• Original: J:134768 Montanez E, et al., Kindlin-2 controls bidirectional signaling of integrins. Genes Dev. 2008 May 15;22(10):1325-30
• All: 2 reference(s)