Mboat4^tm1Jagu
Targeted Allele Detail

Summary

• Symbol: Mboat4^tm1Jagu
• Name: membrane bound O-acyltransferase domain containing 4; targeted mutation 1, Jesus A Gutierrez
• MGI ID: MGI:3790106
• Synonyms: GOAT^-
• Gene: Mboat4 Location: Chr8:34582184-34592336 bp, + strand Genetic Position: Chr8, 20.9 cM
• Alliance: Mboat4^tm1Jagu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:134640
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A 10 kb fragment including the start methionine codon in exon 1 through 208 bp downstream of the stop codon in exon 3 was replaced with a frt-flanked targeting cassette. The targeting cassette was subsequently removed leaving a frt recombinase site in place of the coding region. (J:134640)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mboat4 Mutation: 18 strains or lines available

References

• Original: J:134640 Gutierrez JA, et al., Ghrelin octanoylation mediated by an orphan lipid transferase. Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6320-5
• All: 9 reference(s)